Expresión de búsqueda:
RIBOSOME INACTIVATING PROTEINS
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Ribosome Inactivating Proteins
Descriptor
Español
:
Proteínas Inactivadoras de Ribosomas
Descriptor
Portugués
:
Proteínas Inativadoras de Ribossomos
Sinónimos
Inglés
:
RNA N-Glycosidase
Categoría:
D08.811.277.450.430.700
D12.776.765.710
Definición
Inglés
:
N-Glycosidases that remove adenines from
RIBOSOMAL RNA
, depurinating the conserved alpha-sarcin loop of
28S RIBOSOMAL RNA
. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as
PROTEIN SYNTHESIS INHIBITORS
. They are found in many
PLANTS
and have cytotoxic and antiviral activity.
Acción Farmacológica:
Protein Synthesis Inhibitors
Nota Histórica
Inglés
:
2008(1988)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52713
Identificador Único:
D054788
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS